When Life & Style caught up with Jennifer Aniston in NYC on April 14, the actress hardly looked like someone who was enjoying her stay in the city. Asked how she was doing, a grim-faced Jen simply responded, "I'm hanging in there."

Jen, 40, has always loved NYC, soaking up the shopping and dining at the trendiest spots whenever she's in town. But during this stay, which began in late March, she's kept a remarkably low profile. When she's not on set filming her new romantic comedy, The Baster, she's been holed up in her room at the Greenwich Hotel in Tribeca, ordering room service for most meals.

Why the sudden shut-in behavior? Jen's nemesis, Angelina Jolie, is also shooting a movie -- the spy thriller Salt -- in and around NYC, and an insider close to Jen believes she's being extremely careful to avoid bumping into Angie. "Instead of going out to restaurants where she might run into Angelina, Jennifer is entertaining guests in her hotel suite," the insider says.

For more on how Jen and Angie are avoiding each other, pick up the latest issue of Life & Style, on newsstands now!

Photo Credit: Abaca; Retna