Though typically private, Sara Ramirez is speaking out about an issue close to her heart.

The Grey's Anatomy star came out as bisexual while giving a powerful speech at the 40 to None Summit on Saturday, Oct. 8.

"So many of our youth experiencing homelessness are youth whose lives touch on many intersections — whether they be gender identity, gender expression, race, class, sexual orientation, religion, citizenship status," the actress, who has been married to banker Ryan Debolt since 2012, announced.

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"And, because of the intersections that exist in my own life: Woman, multi-racial woman, woman of color, queer, bisexual, Mexican-Irish American, immigrant, and raised by families heavily rooted in Catholicism on both my Mexican and Irish sides, I am deeply invested in projects that allow our youth’s voices to be heard, and that support our youth in owning their own complex narratives so that we can show up for them in the ways they need us to," she continued.

The star, who left the long-running ABC show earlier this year, played Dr. Callie Torres, who also identified as bisexual and had romances with both men and women throughout her 10-year stint.

Scroll through the gallery below for more celebs who've confirmed they're bisexual!