Brad Pitt and More Celebs Who Left Their Significant Others For Co-Stars!

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Sep 22, 2016 3:15 pm·

By Allison Cacich

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Brad Pitt caused quite the scandal in 2005 when he left wife Jennifer Aniston for his Mr. and Mrs. Smith leading lady, Angelina Jolie.

But he's not the first celeb to fall for a co-star while involved with someone else. Scroll through the gallery below to see which stars have ditched spouses and girlfriends for their onset partners!

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1 of 9

Billy Crudup

The actor left longtime partner Mary-Louise Parker in 2003 — while she was seven months pregnant — for his Stage Beauty costar Claire Danes. They broke up in 2006.

2 of 9

LeAnn Rimes and Eddie Cibrian

Both the actor and the country singer left their spouses after starting an affair on the set of the TV movie, Northern Lights, in 2009. They've been married since 2011.

3 of 9

Marilyn Manson

The rocker left wife Dita Von Teese in 2006 after he began an affair with actress Evan Rachel Wood, who had starred in one of his music videos. The duo got engaged in 2010, but broke it off later that year.

4 of 9

Tori Spelling and Dean McDermott

The actors both left their spouses after starting an affair on the 2005 set of the TV movie Mind Over Murder. They were married in 2006 and have since welcomed four children together.

5 of 9

John Malkovich

The actor divorced wife Glenne Headly after having an affair with costar Michelle Pfeiffer on the set of 1988's Dangerous Liaisons. The duo's relationship didn't last long.

6 of 9

Humphrey Bogart

The actor was 44 when he met his 19-year-old To Have and Have Not costar Lauren Bacall, and the duo began an affair while he was still married to third wife, Mayo Methot. They tied the knot in 1945 just three months after Humphrey's divorce, and were married until his death in 1957.

7 of 9

Elizabeth Taylor and Richard Burton

Both actors were married when they began an affair on the 1962 set of Cleopatra. The duo married nine days after Elizabeth's divorce from Eddie Fisher in 1964, but divorced in 1974. They later reconciled and remarried in 1975, only to divorce again nine months later.

8 of 9

Meg Ryan

After meeting Russell Crowe on the set of 2000's Proof of Life, the actress left husband Dennis Quaid after nine years of marriage. The pair broke up in 2001.

9 of 9

Brad Pitt

The actor was married to Jennifer Aniston when he met Angelina Jolie on the set of 2005's Mr. & Mrs. Smith. The pair was married in 2014 and have six children together. They announced their divorce in September 2016.

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