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Comedian Jim Gaffigan’s Weight Loss Transformation Over the Years After Shedding 50 Pounds

Health & Fitness

Dec 4, 2024 4:16 pm·

By Beth Shilliday

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Actor and comedian Jim Gaffigan made sure his 50-pound weight loss was funny business, discussing the topic in his November 2024 Netflix stand-up special, The Skinny.

The 17 Again star’s weight fluctuated over the years, and he finally got it under control thanks to the type 2 diabetes drug Mounjaro, which many people have turned to for weight loss.

Jim decided to try the semaglutide after reaching 270 pounds. He lost 50 pounds thanks to the medication, gushing to People, “I feel good. I’m just grateful because it’s such a better life.”

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“And that’s some of why I wanted to talk about it, because I almost thought it was kind of odd that people were resistant to talking about it. I don’t think there’s anything wrong with it … it’s just whatever gets you through,” the Full Circle star added.

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2006

Jim bundled up in a sweater and jacket at the Sundance Film Festival.

The My Boys star told People in November 2024 that in his 20’s he “would work out twice a day just to be thin so I could eat. And then as my metabolism slowed down, it became harder and harder, and then my knees started giving out, and then fatigue set in.”

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2010

Jim showed off an impressive weight loss when he performed at Comedy Central’s Night Of Too Many Stars.

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2017

The Unfrosted actor slowly began gaining back weight, as seen here at the Toronto Film Festival. Jim admitted he’s struggled with keeping off the pounds over the years, joking in his 2024 Netflix special, “I’m trying to enjoy being thin because I know I’m going to be fat again. This is not sustainable.”

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2020

Jim revealed in November 2024 that his doctor asked him the year prior if he’d be interested in trying weight loss medication. “She was like, ‘Well, some people are against it.’ And I’m like, ‘I don’t care, I’ll try it.’ My knees hurt and my cholesterol was kind of not great,” he told People.

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2023

Seen here at the Palm Springs International Film Festival premiere of his film Linoleum, Jim revealed he tipped the scales at 270 pounds before going on Mounjaro.

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2024

In addition to using Mounjaro, Jim started eating a low-carb diet and took up growing his own vegetables.

“Growing vegetables makes you more interested in consuming those vegetables, which makes you healthier, which makes you kind of look at what you’re consuming, which makes fast food look like the crap that it is,” he told Men’s Health in November 2024.

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