When it come to plastic surgery in Hollywood, the real question is, who isn't doing it?

Beloved actress Meg Ryan recently debuted her new, erm, face and we're pretty upset about it. Instead of just letting herself age naturally (she's only 53-years old!), the mother-of-two has seemingly had so much work done that there's not a wrinkle in site. Also, smiling looks painful.

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Click through the gallery to see her shocking transformation over time.